Tag : nucleophile

Bromination of Cholesterol and Debromination: Purification of Cholesterol

Written by: Nicholas Connor The purpose of this experiment was to understand alkene-halide reactions by purifying commercial cholesterol. Analysis The purpose of this experiment was to remove the impurities present in commercial cholesterol; to yield pure 5-Cholesten-3B-ol. Bromination was the method chosen to remove traces of 3B-cholestanol, 7-cholesten-3b-ol, and 5,7-cholestadien-3B-ol that were assumed to be present in the sample used. The net reaction of bromination follows: To begin removing the impurities, the cholesterol sample (0.97 g) was dissolved in tert-butyl-methyl-ether […]