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Tag : stereoselectivity

Hydride Reduction Reactions: A Stereoselective Adventure

Written by Ryan Introduction The purpose of this experiment is to investigate the stereoselectivity of various reducing agents in the reduction of a carbonyl group. The first part of this experiment will focus on the stereoselectivity of sodium borohydride, lithium aluminum hydride, and lithium tri-sec-butylborohydride (L-selectride) in the reduction of 4-tert-butylcyclohexanone.1 The second part of this experiment will focus on the stereoselectivity of saccharomyces cerevisiae (baker’s yeast) in the reduction of ketone in ethyl acetoacetate.2 The stereoselectivity of each reducing […]