By: Robert Burns Abstract: The purpose of this experiment was to successfully synthesize dihydrojasmone through a series of synthetic steps starting from levulinic acid. Then, using 1,1’-carbonyldiimidazole (CDI), the acid was turned into a Weinreb amide. After a simple conversion of the carbonyl group to a ketal, the amide was reacted with hexyl magnesium bromide to give the 1,4 diketone. The diketone was then refluxed under basic conditions to afford dihydrojasmone as a light brown liquid (0.06g, 28.0%). All products […]
