Tag : Metal Hydride

Reduction of Ketones Using a Metal Hydride Reagent: 4-tert-Butylcyclohexanol

Written by Breha Objective: The purpose of this experiment is to reduce ketones, 4-tert-Butylcyclohexanone, to form the alcohol, cis and trans-4-tert-Butylcyclohexanol. The reduction of a ketone carbonyl to alcohol is carried out using sodium borohydride. The alcoholic reactions products are isolated by liquid-liquid extractions techniques and purified by preparative gas chromatography. Cis and Trans diastereoisomers are formed in the reduction of the 4-tert-butylcyclohexanone. TLC was also used to monitor the completion of the experiment. Experimental Procedure: Experiment 5B was followed […]