Tag : Substitution Reactions

The Role and Nucleophilicity of Chloride and Bromide Nucleophiles in Both Sn1 and Sn2 Substitution Reactions with Tert-Butanol and 1-Butanol

The Role and Nucleophilicity of Chloride and Bromide Nucleophiles in Both Sn1 and Sn2 Substitution Reactions with Tert-Butanol and 1-Butanol By: Rachel Wolfson*, Louis Kuo, Lisa Holmes, Luciano Santino, Cooper Jamieson ABSTRACT The purpose of this experiment is to determine the relative nucleophilicities of chloride and bromide in both an Sn1 and Sn2 reaction. It also investigates rate law kinetics and solvent effects. Tert-butanol and 1-butanol were reacted separately with equal mixtures of the nucleophiles in order to facilitate both […]

Investigating Substitution Reactions of Various Alcohol-Containing Compounds

By: Kristen Powell, Morgan Sanders, Robert Walker This is a Laboratory Journal of Organic Chemistry Note for synthesis reaction data obtained in the Organic Chemistry Laboratory—All information was experimentally conducted. This article should be used as a reference when conducting your own synthesis reactions. Three reactions containing alcohol groups, on primary and secondary carbons reacting with halide groups have been the topic of investigation through experimental testing. The substitution pathway varied between reactions due to the different structures. Variables such as […]